CURCUMIN, A NATURAL GOLDEN DRUG AND ITS ANTICANCER ASPECTS FROM SYNTHESIS TO DELIVERY: A REVIEW

Abstract

Cancer is a dreadful disease and, in most
cases, leads to death even when it is being
treated. Even though synthetic drugs are
still in use for the treatment of cancer, the
seriousness of the side effects of these
drugs especially anticancer activity. Paper
summarizes the chemistry and biometabolism of curcumin in the human
body. Aim of this review article is to
gather the dispersed efforts of researchers
predominantly in improving the
bioavailability of curcumin. In the present
review, comprehensive literature on
anticancer activity of Curcumin via
combination therapy, structure
modification, synthesis of analogues, novel
delivery systems have been highlighted.
Besides, the review paper explicated
several challenges associated with
Curcumin as an adjuvant chemotherapeutic
agent and emphasizes more on clinical
studies.